I dont really look them up but my favourite is the oat meal.

everything else seems like they try too hard. I used to read C&H everyday but its now so full of overly cliche puns that 4 year olds make up. some of the xkcd ones are ok but... i don't understand a lot of them *blush*

I like this one I found on Smogon called Rare Candy Treatment. It makes fun of a lot of pokemon things we all can agree on. This one is a good example..

Don't really care if I repeat anything already posted in this thread, but here's the list of stuff I follow:

Awkward Zombie (updates on Mondays)
Bob the Angry Flower (Fridays)
Buttersafe (Tuesdays and Thursdays)
Castle Vidcons (once every blue moon)
Cucumber Quest (Sundays and Wednesdays, with occasional bonus updates)
Cyanide & Happiness (every day)
Nedroid Picture Diary (2-3 times a week)
Penny Arcade (every three days)
Rare Candy Treatment (whenever)
XKCD (Mondays, Wednesdays, and Fridays)

Just as a note; if you want to start reading Cucumber Quest, it's much more plot-driven than the other comics on my list, so start reading from page 1.

Nuzlocke, Super Effectice, and BitF have already been posted, so that just leaves me with The Fuzzy Five and Gold Coin Comics. Updates on Monday+Wednesday and I think Tuesday+Thursday. One is about the squishables, who are THE most awesome plushies ever, and the other is for online RPG fans.

Oh dear, time to trim out the Comics folder to the ones appropriate to post here. Every day, Firefox yells at me for trying to open 19 tabs at once...

MegaTokyo - One of the "classic" American-Manga comics. Been reading since high school, not that it takes much when 1 new page a month is a "rapid" update schedule compared to how it's going.
Applegeeks - Pretty much dead, but the artist is quite talented, and the writer's gone on to some other rather popular projects that I haven't got around to reading yet.
MacHall / Three Panel Soul - The college / real life pair of comics. Great stuff for anyone in the 17 - early/mid 20's range.
Misfile - EP already mentioned it. Author's strange quirks of anatomy bug me sometimes, but the general premise and whole "what defines self" theme is pretty cool.
xkcd - The geek comic.
Boxer Hockey - Another "barely updates" one, but a funny story.
Fail Friends - Semi-autobiographical, involving someone from MegaTokyo's forums, which is how I found it.
Hipster Hitler - Just what it says on the tin.
Stupid Fox - Also just what it says on the tin.

A few more adult-oriented ones:
Nerf Now - Various nerdy jokes, lot of TF2 and stuff. Generally silly, sometimes less than entirely appropriate.
Questionable Content - Nothing more visually explicit than you'd find in a PG-13 movie, but some pretty heavy topics and dialog not appropriate for anyone not yet in high school. Also, the degree to which the art has improved over the years is astounding, and going back to view the earlier comics is difficult.

There's a few more on my list that are strictly inappropriate for minors. Which is a shame, cause some of them have, in my opinion, the best stories out of any webcomics I read. They just also happen to feature people running around completely nude for a few pages, spouting off some cleverly colorful language, or dying some particularly gruesome deaths.

I really only read XKCD, VG Cats, Super Effective, Brawl In The Family. I don't really read a lot of Webcomics.

So far (of ones I can post on this topic) I've added Hipster Hitler and Stupid Fox to my list. Another one I've found that I'm starting to get into is El Goonish Shive, which I haven't gotten all the way through on, but is quite absurd. It's pretty funny though.

Also, in case there is anyone else interested, I have found this site: TopWebcomics. Yes, its exactly what it says on the tin. You can vote up your favorites and find new ones to read, which is interesting.

i need to find something new to do dont i ._.

Idk if anyone said this but Flaky Pastry is a good webcomic if you like Tolkien humor.

Manly Guys Doing Manly Things is a hilarious webcomic and featured an awesome Pokemon story arc. http://thepunchlineismachismo.com/archives/99

I read xkcd, VG Cats, Super Effective, and Penny Arcade. I just started reading MegaTokyo from the beginning, and I'm on strip #165 right now.

Regarding xkcd, I'm usually one who understands the jokes but, like most people I don't understand many of the ones on topics I haven't explored yet.

In addition to many of the others already listed, I'm fond of MS Paint Adventures. I recommend starting with Problem Sleuth, but beware it is pretty long. I haven't started Homestuck yet but it has a pretty large following so I'll probably give it a shot soon.

I also like Gun Show a lot. Some of the entries are just so outrageously hilarious.

Hmm ... quite a few of us are following VG Cats & Super Effective I see. As well as Awkward Zombie, so I'll skip those. Hopefully I'll be able to mention a few that you all haven't found yet! And thanks to Shuckle-rock$, I'm now reading Rare Candy Treatment! LOL. Anyway, here's the ones I regularly follow;

The Abominable Charles Christopher (be ready to laugh AND cry - one of the best of the web imho); http://www.abominable.cc/

Bear Nuts (the antics of the bears at the cut-rate zoo); http://www.bearnutscomic.com/

The Book of Biff (okay ... I don't really know what Biff is, but the comic is funny); http://www.thebookofbiff.com/

Tales of a Checkered Man (the adventures of a guy trying to be a super hero - in a town where they're not allowed); http://thecheckeredman.com/

Cleopatra in Spaaaace!!! (teen-aged Cleopatra is taken from ancient Egypt and transported to the future to save ... everything); http://www.cowshell.com/cleopatra/

Dark Legacy comic (WOW comic - funny & quirky ... just like me); http://www.darklegacycomics.com/

Darwin Carmichael is Going to Hell (the adventures of a guy who's karma has been wrecked); http://dcisgoingtohell.com/

Dominic Deegan, Oracle for Hire (the misadventures of ... well an oracle for hire); http://www.dominic-deegan.com/

Edmond Finney's Quest to find the Meaning of Life (the title is a good descriptor ...); http://eqcomics.com/

Eerie Cuties (the tale of a young vampire girl ... who would rather eat chocolate than drink blood); http://www.eeriecuties.com/

Escape from Terra (a more serious sci-fi comic ... excellent story lines); http://www.bigheadpress.com/eft

The Greening Wars (again, good sci-fi, post-apocalyptic bio-war type comic); http://www.drunkduck.com/The_Greening_Wars/

Gunnerkrigg Court (we follow the school years of a young girl discovering magic, adventure and robots); http://www.gunnerkrigg.com/index2.php

Jackie Rose (Jackie Rose is a kind of adventuring/treasure hunting young girl who gets dragged into things she had no idea existed); http://www.jackierosecomic.com/

Life Ain't no Ponyfarm (a girl cartoonist living in an apartment with an elephant, an ex-wrestler mushroom and a pony that doesn't talk); http://sarahburrini.com/en/

Looking for Group (as the name implies, it's loosly based in the WOW world); http://www.lfgcomic.com/

My Sister the Freak (okay, I can't really describe this one ... but there's aliens!); http://www.mysisterthefreak.com/

Sandra and Woo (a young girl and her talking raccoon ... you can't go wrong with talking raccoons ... well, maybe you can); http://www.sandraandwoo.com/

Selkie (a story of adoption ... super cute story and excellent characters); http://www.selkiecomic.com/

Wapsi Square (Monica works in a museum - one day she finds an artifact that is, in fact, an ancient and living god ...); http://wapsisquare.com/

The Zombie Hunters (post-apocalyptic looting in zombie country ...); http://www.thezombiehunters.com/index.php

Zombie Ranch (and then they find that zombies are useful ...); http://www.zombieranchcomic.com/

Every morning I open my Webcomic bookmark with "open all in new tabs"

Awkward Zombie
Dueling Analogs
Gunnerkrig Court
Homestarrunner (dead basically)
Penny Arcade
Saturday Morning Breakfast Cereal
Three panel Soul
XKCD
Hark, A vagrant
Zero punctuation (dunno why I keep this in comics..)
VG cats
Super effective
Questionable Content
Married to the Sea
Nerf Now!
Fanboys
and Cracked! Homepage.

Penny Arcade
VGCats (don't judge me...)
Amazing Super Powers

XKCD
Cyanide and Happiness

I have a folder containing my favorite web comics from both of those.

I am so glad to see that you are in love with web comics. I too am an ardent fan of web comics and some of my favorites are “Arthur, King of time and space”, Achewood, Frentic Funnies, The Adventures of DrMc Ninja and Questionable content. Haven’t heard of Saturday Morning Breakfast Cereal! I’ll be giving it a try.

Web comics are for fags... in case you people weren't aware.

Meh, fine by me.